Wednesday, August 31, 2016

The Vascular Endothelium in Chronic Kidney Disease: A Novel Target for Aerobic Exercise.

The Vascular Endothelium in Chronic Kidney Disease: A Novel Target for Aerobic Exercise.

Exerc Sport Sci Rev. 2016 Jan;44(1):12-9

Authors: Martens CR, Kirkman DL, Edwards DG


Endothelial dysfunction occurs in chronic kidney disease (CKD) and increases the risk for cardiovascular disease. The mechanisms of endothelial dysfunction seem to evolve throughout kidney disease progression, culminating in reduced L-arginine transport and impaired nitric oxide bioavailability in advanced disease. This review examines the hypothesis that aerobic exercise may reverse endothelial dysfunction by improving endothelial cell L-arginine uptake in CKD.

26509484

Read More