Sunday, February 9, 2014

Food-dependent exercise-induced anaphylaxis with negative allergy testing.

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Food-dependent exercise-induced anaphylaxis with negative allergy testing.

BMJ Case Rep. 2014;2014

Authors: Kleiman J, Ben-Shoshan M

Abstract
Food-dependent exercise-induced anaphylaxis (FDEIA) is a disorder where exercise following allergen ingestion triggers anaphylaxis although exercise and allergen exposure are independently tolerated. The diagnosis of FDEIA is based on a characteristic clinical history. The culprit allergen is usually confirmed through the use of skin prick testing (SPT) serum-specific IgE levels and a food-exercise challenge. We present a case of FDEIA suggested by clinical history and open food-exercise challenge with negative specific IgE levels and SPT that highlights the challenges involved in diagnosing and managing this rare disorder.

PMID: 24503659 [PubMed - in process]

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